Friday, February 20, 2009

Therapeutic Writing

Dear bad scientists:

I answered that question. I did the experiment last year. I showed you the data when I got it. No, really, I did and you nodded along as I explained it. But you really didn't get it did you? No, was the experiment too complicated for you? Was the complete lack of correlation too clean? Honestly, I wish you could explain why you feel the need to repeat parts of the experiment, but leave out the necessary controls and then claim correlation. You're wrong. Wrong, wrong, wrong. And the next time you bring it up in a meeting, after me walking you through my experimental design three separate times, I'm going to ignore the fact that our bosses' boss is there and smack you down in an epic fashion. Fair warning and all that good stuff.

And to those of you who refuse to accept that I can design the experiment better than you. That sh*tty data you're trying to pass of as showing a significant effect? Yeah, that graph there that has no labels on the axis. And, yep, that heat map that likewise has no scale. And the things you claim are significantly different without actually including p-values or any statistical measure at all. Yeah, I told you your design wasn't going to work. I told you that nine months ago.

Oh, you did the same experiment ten times? Really, well perhaps you should have tried doing it a few different days instead of using all identical samples on the same day and running it all on the same machine. The differences you see? Yeah, you're just accentuating the noise from the assay method.

Yes, I am pretty sure that's the case. I can take a look at your primary data and demonstrate it. No, no, your primary data, not the crap you have on your slide. Do you understand the difference between primary data and a visual representation of massaged data? Oh, good. Do you have a problem with me looking at your primary data, that look on your face is like I just killed your dog and dressed up in it's skin to parade around the room? I'm pretty sure that we work for the same company and all. Oh, perhaps you're concerned that I'm going to take your data and mis-interpret it and then blather on about it? Yeah, like you did with mine, exactly. Well, fortunately, I am 1) not an imbecile and 2) will ask when I don't understand something.

Yes, yes, I get that you did the experiment ten times, you said so already. Why didn't you do it once, look at the data and then choose the samples that seemed to have the most significant effect so that you could remove experimental biases in the repeat? Oh, it's a lot of work to move the samples around on the plate? Why does your research assistant have her hand over her mouth, but is clearly smiling at me? Is it because it's she who actually has to do the experiment ten incredibly stupid times and appreciates that someone is finally calling you out on this? Do you know what happens when your assistants know that you're an idiot. You're about to find out.

Sincerely,
Tach, Ph.D.

Monday, February 16, 2009

What I Read (What I Will Be Reading?) - Preview

Here are some of the things in my book pile that I plan to get through over the next couple of months.

Some of them I know are going to get a 'Don't Read' rating already. And since I already know that, why am I going through the exercise of reading them? I don't know, but it's partly the reason for the exercise of keeping track of everything that I'm reading.

At any rate:

The Yiddish Policeman's Union - Michael Chabon
American Buffalo - Stephen Rinella
Atmospheric Disturbances
Beware - Richard Laymon

Sunday, February 15, 2009

What I Read - February, 2009 - Part 2

Man in the Dark - Paul Auster - READ

Paul Auster is a terrific writer. You do sort of need to be in the mood, but his stories are always compelling. This is an extremely slim volume but eminently readable.

I do always feel when reading him that I'm missing a big chunk of something, but even what I'm getting I enjoy.

Friday, February 6, 2009

What I Read - February, 2009 - Part 1

Wormwood - Poppy Z. Brite - DON'T READ

I'm always on the lookout for good horror short fiction and am often willing to take a flier on on a collection to see if maybe this is a writer who might provide a source for me. Poppy Z. Brite is not.

I read one of her short stories in Cemetery Dance magazine and it did make me want to try more of her short fiction. I really wish that I hadn't. I'm not a fan of the 'open ended' type of horror fiction that seems to be all the rage in the modern publishing world. I don't really like what I think of as 'vague' horror. And this is the type of horror that Brite writes. So if you enjoy this sort of story, you have something to read. I guess the closest 'main stream' literary analogy would be modern 'magical realism', which is the sort of writing that makes me want to pound a nail through my dick.

At any rate, Poppy Z. Brite is not the next Joe Lansdale (who is probably the best currently writing author of horror short stories), Stephen King (who wrote what is probably the best collection of horror short stories in Skeleton Crew) or Bentley Little (who writes great short horror fiction and terrible novels).